Epstein-Barr Virus Related Polymorphic Posttransplantation Lymphoproliferative Disease in a Patient with Latent Infection of JC Virus.
- Author:
Chang Hun BIN
1
;
Min Su PARK
Author Information
1. Department of Neurology, Yeungnam University College of Medicine, Daegu, Korea. minsupark@ynu.ac.kr
- Publication Type:Case Report
- Keywords:
Epstein-Barr virus;
John Cunningham virus;
Posttransplantation lymphoproliferative disease
- MeSH:
Demyelinating Diseases;
Herpesvirus 4, Human;
Humans;
JC Virus;
Leukoencephalopathy, Progressive Multifocal;
Viruses
- From:Journal of the Korean Neurological Association
2012;30(2):136-140
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Posttransplantation lymphoproliferative disease (PTLD) is an important form of posttransplant malignancy and is typically associated with Epstein-Barr virus (EBV). Progressive multifocal leukoencephalopathy (PML) is a demyelination disease caused by infection of the John Cunningham (JC) virus. Both PTLD and PML occur in the setting of an immunosuppressive state. Differentiating PTLD from PML is important because PTLD can be treated by reducing immunosuppressant agents or anti-B-cell antibody therapy. We report a case of EBV-related PTLD in a patient with latent JC virus.
