Rehabilitation of erectile function following radical prostatectomy.
- Author:
Andrew R MCCULLOUGH
1
Author Information
1. Department of Urology, New York University School of Medicine, New York, NY 10016, USA. andy.mccullough@nyumc.org
- Publication Type:Journal Article
- MeSH:
Alprostadil;
administration & dosage;
Animals;
Erectile Dysfunction;
etiology;
rehabilitation;
Humans;
Male;
Muscle, Smooth;
physiopathology;
Penile Erection;
physiology;
Penis;
innervation;
Peripheral Nerve Injuries;
Phosphodiesterase 5 Inhibitors;
Phosphodiesterase Inhibitors;
administration & dosage;
Prostatectomy;
adverse effects
- From:
Asian Journal of Andrology
2008;10(1):61-74
- CountryChina
- Language:English
-
Abstract:
The concept of muscle rehabilitation after nerve injury is not a novel idea and is practiced in many branches of medicine, including urology. Bladder rehabilitation after spinal cord injury is universally practiced. The erectile dysfunction (ED) experienced after radical prostatectomy (RP) is increasingly recognized as being primarily neurogenic followed by secondary penile smooth muscle (SM) changes. There is unfortunately no standard approach to penile rehabilitation after RP because controlled prospective human studies are not available. This article reviews the epidemiology, experimental pathophysiological models, rationale for penile rehabilitation, and currently published rehabilitation strategies.