Cohort study of 684 pairs of mother-and-child allergic diseases.
- Author:
Hui HUANG
1
;
Feng-ying ZHANG
;
Jing-qing HANG
;
Jie ZHU
;
Rui WANG
;
Pei-feng CHEN
;
Wei-lian GU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Asthma; epidemiology; etiology; genetics; Breast Feeding; Cohort Studies; Eczema; epidemiology; etiology; genetics; Female; Humans; Hypersensitivity; complications; epidemiology; Infant; Infant, Newborn; Logistic Models; Male; Multivariate Analysis; Parents; Pregnancy; Risk Factors; Surveys and Questionnaires
- From: Chinese Journal of Pediatrics 2013;51(3):168-171
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo understand allergic diseases related factors in Changzheng Town, Putuo District infants and young children.
METHODPregnant women registered in Putuo District, Changzheng Town Community Health Service Center Child Health Clinic within the period from January to December, 2008 were enrolled into this survey, a questionnaire survey. The infants were followed up from birth to 2 years of age. The mother and child survey was conducted for 746 pairs, and 684 pairs had complete data. SAS V9.1 statistical software was used for data processing and statistical analysis.
RESULTThe survey showed that prevalence of eczema, allergic rash, and wheezing was 27.9%, 18.9%, and 3.9%, respectively. Multivariate logistic regression analysis showed that allergy in either parent and addition of foods other than milk in infants before 4 months of age were risk factors for eczema; allergy in either parent was also risk factors for allergic rash. Exclusive breastfeeding from birth to 6 months of age was a protective factor for wheezing in infants. Other factors such as parental history of asthma, vitamin supplements to the mothers during pregnancy, mothers' special diet habits, calcium level of infants, etc. had no significant correlation with allergic disorders in infants.
CONCLUSIONThe risk factors for allergic disorders in infants included allergy in either parent and dietary factors of the infants themselves (prematurely adding other foods). Breastfeeding (for 0 - 6 months of age) was a protective factor for infants' wheezing.