Relationship between extracapsular spread of cervical metastatic lymph node and cervical recurrence in oral cancer patients.
- Author:
Shi-Qi ZOU
1
;
Chi MAO
;
Yan GAO
;
Xin PENG
;
Xiu-Wen LUAN
;
Ying-Bin YAN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; pathology; Female; Follow-Up Studies; Humans; Logistic Models; Lymph Nodes; pathology; Lymphatic Metastasis; pathology; Male; Middle Aged; Mouth Neoplasms; pathology; Neck; pathology; Neoplasm Recurrence, Local; Prognosis; Retrospective Studies
- From: Chinese Journal of Stomatology 2007;42(9):541-543
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the relationship between extracapsular spread (ECS) of cervical metastatic lymph node and the recurrence in patients with oral squamous cell carcinoma (OSCC).
METHODSThe medical records of 74 OSCC patients with histologically confirmed cervical lymph node metastasis were reviewed. They were divided into 2 groups, ECS positive (ECS+) and ECS negative (ECS-). The treatment results were followed up. Statistical analysis, with chi-square test, and multiple logistic regression was conducted.
RESULTSThe overall recurrence rates for pN+/ECS- and pN+/ECS+ patients were 47.6% and 75.0%, respectively, and the cervical recurrence rates for pN+/ECS- and pN+/ECS+ patients were 9.5% and 46.9%, respectively (P < 0.001). Multivariate analysis showed that ECS was one of the independent prognosis factors for cervical recurrence.
CONCLUSIONSExtracapsular spread significantly increased both overall and cervical recurrence rates, and ESC may be a prognosis factor for OSCC patients.
