Research Progress in Seeding Cells of Peripheral Nerve.
- Author:
Gengqiang SHI
;
Yi HU
- Publication Type:Journal Article
- MeSH:
Axons;
Cell Differentiation;
Cells, Cultured;
Mesenchymal Stromal Cells;
Myelin Sheath;
Nerve Regeneration;
Neural Stem Cells;
Oligodendroglia;
Peripheral Nerve Injuries;
Schwann Cells;
Stem Cells
- From:
Journal of Biomedical Engineering
2015;32(2):470-474
- CountryChina
- Language:Chinese
-
Abstract:
Seeding cells play an important role in the peripheral nerve damage repair. Seeding cells studied conse- quently in peripheral nerve are Schwann cells, bone marrow mesenchymal stem cells and neural stem cells. Schwann cells, the first seeding cells, are various unique glial cells in the peripheral nervous system, which can form the myelin sheath for insulation and package of the neuron projecting axons in the peripheral nervous system so that the conduction velocity of the nerve signal was accelerated. It can be proved that Schwann cells played an important role in the maintenance of peripheral nerve function and in the regeneration process after peripheral nerve injury. The second, bone marrow mesenchymal stem cells are the various mesenchymal stem cells mainly exist in the systemic connective tissues and organs. These functional stem cells are often studied at present, and it has been found that they have exuberant proliferation and differentiation potentials. Neural stem cells, mentioned the third in sequence, are the kind of pluripotent cells with multi-directional differentiation, which could conduct the self-renewal function, and generate and differentiate neurons, astrocytes and oligodendrocytes through asymmetric cell division. These three types of seed cells are discussed in this paper.
