Research Progress of the Regulation Function of Epigenetics on Bone Marrow Mesenchymal Stem Cells.
- Author:
Chen ZHIHAO
;
Shubin FANG
;
Jing TIAN
- Publication Type:Journal Article
- MeSH:
Acetylation;
Bone and Bones;
DNA Methylation;
Epigenesis, Genetic;
Hematopoietic Stem Cells;
Histones;
Humans;
Mesenchymal Stromal Cells;
cytology;
MicroRNAs;
Myocardium;
RNA, Small Interfering;
Wound Healing
- From:
Journal of Biomedical Engineering
2015;32(3):680-683
- CountryChina
- Language:Chinese
-
Abstract:
The regulation of epigenetics on bone marrow mesenchymal stem cells (BMSCs) has been a research hot spot in medical area. This paper mainly summarizes the progress of the regulation of DNA methylation, histone acetylation, small interfering RNA (siRNA) induced gene silence and microRNA (miRNA) on BMSCs. Our analysis shows that the regulation of epigenetics on BMSCs plays a significant role in the repair of bone tissue, nervous tissue and cardiac muscle.
