Modeling of human colonic blood flow for a novel artificial anal sphincter system.
- Author:
Peng ZAN
1
;
Guo-zheng YAN
;
Hua LIU
Author Information
- Publication Type:Journal Article
- MeSH: Anal Canal; blood supply; physiology; Blood Flow Velocity; physiology; Computer Simulation; Computer-Aided Design; Equipment Failure Analysis; Humans; Models, Biological; Prostheses and Implants; Prosthesis Design
- From: Journal of Zhejiang University. Science. B 2008;9(9):734-738
- CountryChina
- Language:English
- Abstract: A novel artificial anal sphincter system has been developed to simulate the normal physiology of the human anorectum. With the goal of engineering a safe and reliable device, the model of human colonic blood flow has been built and the relationship between the colonic blood flow rate and the operating occlusion pressure of the anorectum is achieved. The tissue ischemia is analyzed based on constitutive relations for human anorectum. The results suggest that at the planned operating occlusion pressure of less than 4 kPa the artificial anal sphincter should not risk the vascularity of the human colon.
