Clinical thinking about treating acute ischemic stroke by targeting the neurovascular unit of Chinese medicine.
- Author:
Ya-Ling LEI
1
;
Qing LIU
;
Yi LUO
Author Information
1. Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510405, China. lyzmbb@qq.com
- Publication Type:Journal Article
- MeSH:
Brain Ischemia;
drug therapy;
Drugs, Chinese Herbal;
administration & dosage;
therapeutic use;
Humans;
Neurons;
Phytotherapy;
methods;
Stroke;
drug therapy
- From:
Chinese Journal of Integrated Traditional and Western Medicine
2013;33(9):1276-1280
- CountryChina
- Language:Chinese
-
Abstract:
Neurovascular unit (NVU) concept proposed for the treatment of acute ischemic stroke (AIS) provides a new target, i.e., we should target as an integrity including neurons, glia, and microcirculation, thus supplementing limitations of previous treatment targeting neurons or blood vessels alone. Meanwhile, many clinical trials have failed after NVU protection against AIS drug research has developed at home and abroad. Chinese medicine has multi-component, multi-target, and overall regulation advantages, and is in line with clinical requirement for overall treatment targeting multiple targets of NVU. Currently clinical studies of Chinese medicine treatment of AIS targeting NVU are few. Standardized and systematic clinical efficacy evaluation is lack. Clinical studies for improving AIS-NVU injured blood markers by Chinese medicine are rarer. We hope to pave the way for performing clinical studies on Chinese medicine treatment of AIS targeting NVU.
