Biological sample preparation via self-assembly methods for atomic force microscopy studies.
- Author:
Congzhou WANG
1
;
Wang JIANHUA
Author Information
1. College of Bicengineering, Chongqing University, Chongqing 400044, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Cells;
DNA;
analysis;
Humans;
Lipids;
analysis;
Microscopy, Atomic Force;
methods;
Proteins;
analysis;
Specimen Handling;
methods
- From:
Journal of Biomedical Engineering
2011;28(3):618-622
- CountryChina
- Language:Chinese
-
Abstract:
As an effective tool to study proteins, nucleic acids, cells and other biological samples, atomic force microscope (AFM) has been widely used in various fields of life science. Biological sample preparation via self-assembly is the precondition of the research. In this paper, common self-assembly methods of biological samples such as proteins, lipid films, DNA and cells for AFM studies are reviewed, and how the samples to be well attached to a substrate using appropriate, nondestructive methods is discussed. The trends towards the development in the future are also looked into.
