Warty Squamous Cell Carcinoma of the Vulva in Older Women: Association with Human Papillomavirus.
10.3349/ymj.2005.46.1.155
- Author:
Yong Hyun JANG
1
;
You Chan KIM
;
Eun So LEE
Author Information
1. Department of Dermatology, Ajou University School of Medicine, Suwon, Korea. esl@ajou.ac.kr
- Publication Type:Case Report
- Keywords:
Wart;
squamous cell carcinoma;
human papillomavirus;
DNA microarray
- MeSH:
Aged;
Carcinoma, Squamous Cell/pathology/*virology;
Female;
Humans;
Papillomavirus Infections/*complications/pathology;
*Papillomavirus, Human;
Skin Neoplasms/pathology/*virology;
Vulvar Neoplasms/pathology/*virology
- From:Yonsei Medical Journal
2005;46(1):155-158
- CountryRepublic of Korea
- Language:English
-
Abstract:
Warty squamous cell carcinoma (WSCC), a rare variant of squamous cell carcinoma occurring in younger women, is primarily associated with human papillomavirus (HPV) infection. Although WSCC appears to exhibit less aggressive behavior than typical well-differentiated squamous cell carcinoma, it bears the risk of regional metastasis. Accordingly, WSCC should be differentiated from other verruciform neoplasms. We describe a rare case of WSCC with a short disease duration occurring in a woman of old age. We found the presence of HPV DNA different from other well-known types of high risk and low risk HPV by DNA chip microarray. These results suggest that various types of HPV can be associated with the pathogenesis of WSCC.
