Structure and adsorption characterization of SBA-16 and functionalized materials.
- Author:
Zongfu ZHENG
1
;
Guiyuan GUO
;
Yongpeng HU
;
Fuying FENG
;
Guoyan XU
;
Hong TAN
Author Information
1. 476 Hospital, PLA, Fuzhou 350002, China. fuhos@163.com
- Publication Type:Journal Article
- MeSH:
Adsorption;
Drug Carriers;
chemistry;
Porosity;
Silicon Dioxide;
chemistry;
Surface Properties
- From:
Journal of Biomedical Engineering
2011;28(4):768-773
- CountryChina
- Language:Chinese
-
Abstract:
In this study we synthesized a micro- and mesoporous material, SBA-16. And later on we functionalized it with octyltrimethoxysilane and octadecyltrimethoxysilane, respectively. The materials of SBA-16 and its functionalized form were characterized by nitrogen adsorption isotherms at 77K, small angle X-ray scattering (SAXS), Fourier-transform infrared (FT-IR), thermal gravimetric analysis (TGA), and adsorption isotherms of single component n-heptane, toluene and water vapour. The data of FT-IR and TGA demonstrated the successful chemical modification of surface and porous wall of SBA-16 with different hydrocarbon chains. The results of SAXS, nitrogen adsorption at 77K, and adsorption isotherms of probe molecules revealed that the functionalized SBA-16 materials possessed relatively less regularity, smaller BET surface area and pore volumes, and lower adsorption capacities for the probe molecules compared to the original SBA-16. However, the functionalized SBA-16 materials showed much less affinity to polar molecules such as water. This work provides useful fundamental information for future study of novel mesoporous silica materials as potential drug delivery carriers.
