Study of blood compatibility on TiO2 coated biomedical Ni-Ti shape memory alloy.
- Author:
Shuchun GAO
1
;
Yuchun ZHAI
;
Jinling HU
Author Information
1. Academiy of Metallurgy and Material, Northeastern University, Shenyang 110004, China. gaochun4169@263.net
- Publication Type:Journal Article
- MeSH:
Alloys;
chemistry;
Blood Coagulation;
Coated Materials, Biocompatible;
chemistry;
Humans;
Materials Testing;
Nickel;
chemistry;
Platelet Adhesiveness;
Stents;
Surface Properties;
Titanium;
chemistry
- From:
Journal of Biomedical Engineering
2011;28(5):968-1000
- CountryChina
- Language:Chinese
-
Abstract:
We coated a thin TiO2 film on the surface of Ni-Ti shape memory alloy by activated sputter method in the present work. The blood platelet adherence and antithrombogenicity of the TiO2-coated Ni-Ti alloy were evaluated. The results showed that the platelets on the TiO2-coated Ni-Ti alloy were fewer than those on 316L stainless steel, and no agglomeration or distortion for the platelets on the coated alloy was found, which means less probability of blood coagulation for the alloy. The coagulation time on the coated Ni-Ti shape memory alloy was longer than that on the 316L. Compared with that on the 316L stainless steel, the TiO2 coated Ni-Ti shape memory alloy showed better blood compatibility, indicating that the Ni-Ti alloy with TiO2 coating is a kind of ideal biomedical materials with high clinical value.