Percutaneous sonography-guided radiofrequency ablation in the management of parathyroid adenoma.
- Author:
Shuang-ying XU
1
;
Ya WANG
;
Qiong XIE
;
Hong-yan WU
Author Information
1. Department of Endocrinology, Jingzhou First People's Hospital, Yangtze University, 8 Hang-Kong Street, Jingzhou, Hubei 434000, China. hongyan_wu2003@yahoo.com.cn
- Publication Type:Case Reports
- MeSH:
Adenoma;
complications;
surgery;
Catheter Ablation;
Humans;
Hyperparathyroidism;
etiology;
surgery;
Male;
Middle Aged;
Parathyroid Neoplasms;
complications;
surgery;
Parathyroidectomy;
methods;
Ultrasonography, Interventional
- From:Singapore medical journal
2013;54(7):e137-40
- CountrySingapore
- Language:English
-
Abstract:
Parathyroid adenoma is a major cause of primary hyperparathyroidism. Treatment usually involves the surgical removal of one or more parathyroid glands. However, specific localising techniques have boosted the development of nonsurgical, minimally invasive procedures, such as percutaneous radiofrequency ablation (RFA) under ultrasonographic guidance, which are gaining popularity as a method of treatment. This paper reports two male patients who presented with hypercalcaemia (highest serum calcium level 4.56 mmol/L and 4.57 mmol/L, respectively) and hyperparathyroidism (highest serum parathyroid hormone [PTH] level 772 ng/L and > 1,900 ng/L, respectively) due to solitary parathyroid adenoma. Four days after percutaneous RFA, the serum calcium levels in both patients decreased and PTH levels showed a significant decreasing trend. Both patients recovered well with normal levels of calcium and improvement of symptoms. Thus, we conclude that RFA may be a safe and effective therapeutic option in the treatment of parathyroid adenoma.