Clinicopathologic study of 25 cases of placental chorioangioma.
- Author:
Aichun WANG
1
;
Yaqi MA
;
Yun WANG
;
Yingnan WANG
;
Junling XIE
;
Li WANG
;
Jing YUAN
;
Yiqun GU
;
Aijun LIU
2
;
E-mail: ALIU301@126.COM.
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Diagnosis, Differential; Endothelial Cells; pathology; Female; Fetal Death; Hemangioma; pathology; Humans; Infant, Newborn; Placenta; pathology; Placenta Diseases; pathology; Pregnancy; Pregnancy Complications, Neoplastic; pathology; Stillbirth
- From: Chinese Journal of Pathology 2015;44(8):600-602
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the clinicopathological characteristics, diagnostic criteria and differential diagnosis of placental chorioangioma.
METHODSTwenty-five cases of placental chorioangioma were analyzed for their clinical data, histomorphology and immumohisto chemical staining. Relevant literature was reviewed.
RESULTSThe average age of the 25 patients was 29 years. Fourteen patients had full-term pregnancy, 10 had preterm labor, and 1 had intrauterine fetal death. Nineteen patients had pregnancy complications. The tumors presented as red or dusty pink nodules with clear borders. The tumor size ranged from 1 to 16 cm. Microscopically, the tumors possessed abundant capillaries or cavernous blood spaces lined by hyperplastic endothelial cells. These cells were positive for CD34 and Ki-67 index < 10%.
CONCLUSIONSPlacental chorioangioma is a rare benign tumor of the placenta, and is associated with various pregnancy complications. Misdiagnosis of cell-rich type tumor should be avoided.
