Efficacy and Safety of Intravenous Propofol Anesthesia during Transrectal Ultrasound-Guided Prostate Biopsy.
10.4111/kju.2009.50.8.757
- Author:
Kyung Suk CHA
1
;
Seung Wook LEE
;
Jeong Man CHO
;
Jeong Yoon KANG
;
Tag Keun YOO
Author Information
1. Department of Urology, Eulji University School of Medicine, Seoul, Korea. ytk5202@eulji.ac.kr
- Publication Type:Original Article
- Keywords:
Prostate;
Biopsy;
Pain;
Propofol
- MeSH:
Anesthesia;
Biopsy;
Hematuria;
Humans;
Imidazoles;
Lidocaine;
Male;
Needles;
Nitro Compounds;
Propofol;
Prostate
- From:Korean Journal of Urology
2009;50(8):757-761
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Transrectal ultrasonography (TRUS)-guided prostate biopsy causes fear and pain in 65% to 90% of patients. This study was designed to evaluated the use of intravenous propofol anesthesia during TRUS-guided prostate biopsy. MATERIALS AND METHODS: Between January 2006 and June 2008, 195 men undergoing a transrectal prostate biopsy were divided into 2 groups according to anesthetic technique. Group A consisted of 99 patients who received intravenous propofol infusion through an 18 gauge needle during TRUS-guided prostate biopsy. Group B consisted of 96 patients who intrarectally received 10 ml of 2% lidocaine gel 10 minutes before TRUS-guided prostate biopsy. Pain scores were assessed on a visual analogue scale immediately after prostate biopsy. RESULTS: The pain score was significantly reduced in group A compared with group B. There was a significant difference in the mean pain score between the 2 groups (1.0+/-1.3 in group A versus 2.9+/-2.0 in group B; p<0.01). Also, there was a significant difference in the willingness to undergo rebiopsy between the 2 groups (83.8% in group A versus 17.7% in group B; p<0.01). However, the complication rates were not significantly different between the 2 groups. Gross hematuria was found in 14% of group A patients and 18% of group B patients. CONCLUSIONS: Our results proved the advantage of intravenous propofol anesthesia during TRUS-guided prostate biopsy. Intravenous propofol infusion can be a safe and simple technique that significantly reduces pain during TRUS-guided prostate biopsy.
