Two Cases of Familial Hypokalemic Periodic Paralysis.
- Author:
Kwang Kuk KIM
1
;
Jae Hong LEE
;
Sang Soo LEE
;
Jae Kyu ROH
;
Sang Bok LEE
;
Ho Jin MYUNG
Author Information
1. Department of Neurology, College of Medicine, Seoul National University, Korea.
- Publication Type:Case Report
- Keywords:
Familial Hypokalemic Periodic Paralysis;
polyphasic motor unit potential. AD.;
MUAPs
- MeSH:
Family Characteristics;
Humans;
Hypokalemic Periodic Paralysis*;
Paralysis;
Potassium
- From:Journal of the Korean Neurological Association
1990;8(1):180-184
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Two patients of a family, suffenng from frequent periodic paralysis, were evaluated. Their family history reveals seven affected members in three generations, with autosomal dominance pattern. Their earliest symptoms were noticed between 10-13 years of age. The serum potassium level fell during the attack. EMG demonstrated progresslve reduction in numer of motor units and drop off in the response of muscle fibers to stimuli. These findings were consistent with familial hypokalemic periodic paralysis. The clinical features, electron microscoscopic findings, and pathogenesis were also described.
