Study on preparation of refined Xiong-gui sustained release pills.
- Author:
Hui LI
1
;
Bao-lin BIAN
;
Fan-yun MENG
;
Yi-tao WANG
Author Information
- Publication Type:Journal Article
- MeSH: 4-Butyrolactone; analogs & derivatives; analysis; Angelica sinensis; chemistry; Delayed-Action Preparations; Drug Combinations; Drugs, Chinese Herbal; administration & dosage; chemistry; isolation & purification; Ligusticum; chemistry; Plants, Medicinal; chemistry; Technology, Pharmaceutical; methods
- From: China Journal of Chinese Materia Medica 2005;30(10):747-749
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo optimize the molding formula of refined Xiong-gui sustained release pills, types and assorted dosages of water-soluble and non water-soluble drug carrier were studied.
METHODAn orthogonal design was performed to sift the pill formulation. The processing conditions were determining in terms of roundness, hardness, viscosity, fluidity, easily drop.
RESULT AND CONCLUSIONAccording to the final optimal formula, the amount of drug release can be detected instantly, while remaining over 80% at 10 h.
