Optimization study on extraction technology of the seed of Ziziphus jujuba var. spinosa by orthogonal design with multi-targets.
- Author:
Xiao-liang WANG
1
;
Yu-jie ZHANG
;
Ming-xia CHEN
;
Ze-feng WANG
Author Information
- Publication Type:Journal Article
- MeSH: Drugs, Chinese Herbal; chemistry; isolation & purification; Ethanol; Flavones; analysis; Plants, Medicinal; chemistry; Saponins; analysis; Seeds; chemistry; Technology, Pharmaceutical; methods; Ziziphus; chemistry
- From: China Journal of Chinese Materia Medica 2005;30(10):753-755
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo optimize extraction technology of the seed of Ziziphus jujuba var. spinosa with the targets of the total saponin, total jujuboside A and B and total flavonoids.
METHODIn the method of one-way and orthogonal tests, ethanol concentration, amount of ethanol, extraction time and extraction times were the factors in orthogonal test, and each factor with three levels.
RESULTEthanol concentration and extraction times had significant effect on all the targets, other factors should be selected in accordance with production practice.
CONCLUSIONThe best extraction technology is to extract for three times with 8 fold ethanol solution (60%), and 1.5 h each time.
