The effect of preparation method on the quality of shen-mai injection.
- Author:
Yong-jiang WU
1
;
Qin-min CUI
;
Yi-yu CHENG
Author Information
- Publication Type:Journal Article
- MeSH: Chromatography, High Pressure Liquid; methods; Drug Combinations; Drugs, Chinese Herbal; administration & dosage; chemistry; isolation & purification; Ginsenosides; analysis; Injections; Ophiopogon; chemistry; Panax; chemistry; Plants, Medicinal; chemistry; Quality Control; Saponins; analysis; Technology, Pharmaceutical; methods
- From: China Journal of Chinese Materia Medica 2005;30(9):662-665
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the effect of different preparation method on the quality of Shen-mai injection.
METHODThe Shen-mai injection samples were prepared using three different methods. Fingerprints of Shen-mai extracts red ginseng, and its intermediates were obtained using an HPLC analytical procedure. The contents of ginsenoside Rg1, Rc and Rb1, and the gross saponins of Shen-mai extract were quantitatively mensured with HPLC procedures.
RESULTThere was significant difference in fingerprints and chemical contents of the injections prepared by the three different methods.
CONCLUSIONThe quality of Shen-mai injection was greatly influenced by the preparation method. HPLC fingerprinting method can be applied for the determination of the Shen-mai preparations.
