Experimental study on antidiabetic effect of the total flavonoids in Leucaena seeds.
- Author:
Xue-Jian LI
1
;
Jia-Gang DENG
;
Zhen-Lin QIN
;
Hai-Bin HUANG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Blood Glucose; metabolism; Diabetes Mellitus, Experimental; blood; Epinephrine; Fabaceae; chemistry; Flavonoids; isolation & purification; pharmacology; Hyperglycemia; blood; chemically induced; Hypoglycemic Agents; isolation & purification; pharmacology; Male; Mice; Plants, Medicinal; chemistry; Seeds; chemistry
- From: China Journal of Chinese Materia Medica 2005;30(11):842-844
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the hypoglycemic effect of the total flavonoids in Leucaena seeds(TF).
METHODExperimental observation was performed by using various diabetic mice induced by alloxan, adrenalin, etc.
RESULTTF could significantly lower the blood glucose levels in Alloxan model mice, adrenalin model mice and hyperglycemic mice, while had no hypoglycemic effect on the normal mice.
CONCLUSIONThe total flavonoids in Leucaena seeds has hypoglycemic effect in diabetic model mice.