Research on hemostatic effect of total saponins of yinfenglun.
- Author:
Dai-Yin PENG
1
;
Qing-Yun LIU
;
Min DAI
;
Xiao-Mei ZI
;
Xian-Xiang XU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Bleeding Time; Dogs; Drugs, Chinese Herbal; isolation & purification; pharmacology; Female; Hemostatics; pharmacology; Lamiaceae; chemistry; Male; Mice; Partial Thromboplastin Time; Plant Components, Aerial; chemistry; Plants, Medicinal; chemistry; Prothrombin Time; Rabbits; Rats; Rats, Wistar; Saponins; isolation & purification; pharmacology; Whole Blood Coagulation Time
- From: China Journal of Chinese Materia Medica 2005;30(12):909-912
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo research the hemostatic effect of total saponins of Yinfenglun.
METHODBleeding time and volume were deteminded in mice after tails being cut. Clotting times were researched on mice, rats and dogs. Hemostatic mechanism total saponins of Yinfenglun were studied on plasma recalcified time, PT, KPTT and ELT.
RESULTTSY at different doses could markedly shorten bleeding time, reduce bleeding volume in mice. TSY also could shorten clotting time of mouse, rat and dog. TSY could influence both intrinsic coagulatian system and extrinsic coagulatian system,and had no effect of antifibrinolysis.
CONCLUSIONThere were obvious hemostatic effect of total saponins of Yinfenglun.
