Studies on chemical constituents in the seeds of Nigella glandulifera.
- Author:
Yu-ming LIU
1
;
Jun-shan YANG
;
Qing-hua LIU
Author Information
- Publication Type:Journal Article
- MeSH: Glycosides; chemistry; isolation & purification; Molecular Conformation; Molecular Structure; Nigella; chemistry; Oleanolic Acid; analogs & derivatives; chemistry; isolation & purification; Plants, Medicinal; chemistry; Saponins; chemistry; isolation & purification; Seeds; chemistry; Sitosterols; chemistry; isolation & purification
- From: China Journal of Chinese Materia Medica 2005;30(13):980-983
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the chemical constituents in the seeds of Nigella glandulifera.
METHODThe chemical constituents were isolated and repeatedly purified on silica gel column. They were identified and structurally elucidated by means of physio-chemical constants and spectral analysis.
RESULTNine compounds were identified as nigellamose (I), alpha-hederin (II), 3-O-[beta-D-xylopyranosyl-(1-->3)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinpyranosyl]-hederagenin (III), sucrose (IV), stearic acid (V), 1-O-hexadecanolenin (VI), beta-sitosterol (VII), daucosterol (VIII) and p-hydroxybenzoic acid (IX).
CONCLUSIONI, II, III, VI, VIII and IX were obtained from the plant for the first time, and I is a new compound.