Research on effect of total saponins of yinfenglun on uterine.
- Author:
Dai-yin PENG
1
;
Qing-yun LIU
;
Min DAI
;
Xiao-mei ZI
;
Xian-xiang XU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Estradiol; blood; Female; Inflammation; pathology; Lamiaceae; chemistry; Mice; Organ Size; drug effects; Plants, Medicinal; chemistry; Progestins; blood; Rabbits; Random Allocation; Rats; Rats, Wistar; Saponins; isolation & purification; pharmacology; Uterine Contraction; drug effects; Uterine Diseases; pathology; Uterus; anatomy & histology
- From: China Journal of Chinese Materia Medica 2005;30(13):1006-1008
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo research the effect of total saponins of Yinfenglun on uterine.
METHODModels of uterine inflammation were established to observe the effect of total saponins of Yinfenglun. Uterine contractive effects were studied on rats in vitro and on rabbit in vivo. Weight of uterus and levels of estrogen and progestogen were determined.
RESULTTotal Saponins of Yinfenglun had the ameliorated tendency to metritis of model rats, and increased the contractive range and motorricity of uterine of rats in vitro and of rabbit in vivo. The effect to uterus in vivo maintained longer. Total saponins of Yinfenglun could increase the weight of uterus and have an increased tendency on the content of estrogen, but not the level of progestogen.
CONCLUSIONThere are obvious effects on uterine of total saponins of Yinfenglun, which are related to its clinical use.
