Clinical Study of Vitiligo.
- Author:
Hee Joon YU
;
Kyung Chan PARK
;
Jong Seong AHN
;
Jeong Gu LIM
;
Tae Eun KWON
;
Woo Seok KOH
;
Jae Hak YOO
;
Seung Chul LEE
;
Byung Su KIM
;
Un Cheol YEO
;
Gwang Yeol JOH
- Publication Type:Original Article
- Keywords:
Vitiligo;
Clinical study
- MeSH:
Age of Onset;
Hair;
Humans;
Male;
Skin;
Solar System;
Thorax;
Thyroid Diseases;
Vitiligo*
- From:Korean Journal of Dermatology
1998;36(6):1037-1042
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Vitiligo is an acquired depigmentary disorder of the skin and hair. The etiology is unknown, however an autoimmune hypothesis is favored. OBJECTIVE: We performed this study to develop a better understanding of the clinical features of vitiligo patients. METHOD: We evaluated clinical manifestations of 1203 vitiligo patients(556 males and 647 females). RESULTS AND CONCLUSIONS: 1. The mean age of onset and that of the first visits made by patients were 22.9+/-18 and 27.9+/-19 years, respectively. 2. The face(37.4%) was the most common site of initial involvement. In decreasing order of frequency, the common sites of involvement were the face and neck(65.9%), thorax and abdomen(42.9%), upper extremities(42.3%). 44.5% of the cases had the vulgaris type, 26.1% the focal type, and 21.1% the segmental type. During the three months before a visit, 44% of patients experienced progression of disease. Within one year, about 75% of patients reported that the disease had progressed. 3. Precipitating or aggravating factors such as trauma(13.1%), psychological stress(9.2%), sun light (2.8%) and pregnancy(2.5%), were found in 30.9% of patients. Thyroid disease was the most common associated disease.