Quaternion-based Characterization of Protein α Helix.
- Author:
Yonghong XU
;
Zefei CHU
- Publication Type:Journal Article
- MeSH:
Algorithms;
Databases, Protein;
Models, Molecular;
Protein Structure, Secondary;
Proteins;
chemistry
- From:
Journal of Biomedical Engineering
2016;33(1):155-160
- CountryChina
- Language:Chinese
-
Abstract:
This paper proposes a method based on quaternion for characterization a helix of proteins. The method defines the parameter called Quaternion Helix Axis Spherical Distance (QHASD) on the basis of mapping protein Cα frames' helical axis onto a unit sphere, and uses QHASD to characterize the a helix of the protein secondary structure. Application of this method has been verified based on the PDBselect database, with an a helix characterization accuracy of 91.7%. This method possesses significant advantages of high detection accuracy, low computation and clear geometric significance.
