Numerical simulation on evolution and control of spiral wave in heart.
- Author:
Li LIU
1
;
Li LI
;
Guangcai ZHANG
;
Guangrui WANG
;
Zhi QU
Author Information
1. Department of Biophysics, China Medical University, Shenyang 110001, China.
- Publication Type:Journal Article
- MeSH:
Action Potentials;
physiology;
Computer Simulation;
Heart;
physiopathology;
Humans;
Models, Cardiovascular
- From:
Journal of Biomedical Engineering
2007;24(3):485-487
- CountryChina
- Language:Chinese
-
Abstract:
In this paper, the numerical simulation for evolution and control of spiral waves in 2D cardiac excitable media is performed; it can be represented as modified FitzHugh-Nagumo (FHN) model by selecting suitable parameter values. When the plane wave being cut, the system can evolve into a spiral wave. The excitability of media can produce effect on the stability of spiral wave. When the excitability is greater than the critical value, the spiral wave core and period tend towards infinity and disappear. The drifting ways of spiral wave tip are different (meandering) in various driving frequencies when one spiral wave is driven by uniform periodic small current. When period T is below or above the resonance period of spiral wave, the spiral wave is in its pedaflower or pediflower orbit, and if the driving period precisely equals the resonance period, the spiral wave tip drifts along a straight line.
