Evaluation of clinical manifestations and treatment of rodenticide poisoning
- Author:
Xuan Thi Dang
- Publication Type:Journal Article
- Keywords:
toxication
- MeSH:
Poisoning;
Rodenticides
- From:Journal of Medical Research
1998;8(4):6-14
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Study on 112 patients who were admitted to ICU & PCC, Bachmai hospital from 1998 to 2001 due to rodenticide poisoning, we has shown that: rodenticide poisoning was a very common poisoning with high complication and mortality (8%); cardiac arrhythmia were usually the direct cause of death, especially in patients who ingested the white colored agent. The main clinical manifestations of rodenticide poisoning were neuromuscular symptoms (convulsion 49.1%, coma 32.14%, agitation 43.8%, hypereflexia 67.9% hypertonia 59.8%, mental disorders, rhabdomyolysis 33.9%); digestive symptoms (nausea, vomiting, abdominal pain 57.1%); respiratory failure (22.3%); cardiovascular compromise (hypertension 12.5%, disarrythmias 7.14%), acute renal failure (7.14%); hepatic dysfunction (elevated AST 72%, ALT 48%, bilirubin 34.48%); electrolyte disorders (hypocacemia 100%, hyponatremia 20.5%, hypokalemia 29.5%); hematological changes (leukocytosis 52.7%, elevated neutrophil 65.2%); metabolic disorders (hyperuricemia 26.1%, hyperglycemia 23.2%). The patient management should be an anticorrosion therapy, airway management, fluid infusion and early forced dieresis for the prevention of ARF, other critical care and monitoring.