Anaplastic Transformation of Metastatic Papillary Thyroid Carcinomas in the Cervical Lymph Nodes: Report of 3 Cases.
10.16956/kjes.2008.8.3.210
- Author:
Tae Yon SUNG
1
;
Soon Won HONG
;
Sang Wook KANG
;
Seung Chul LEE
;
Jong Ju JEONG
;
Yong Sang LEE
;
Kee Hyun NAM
;
Hang Seok CHANG
;
Woong Youn CHUNG
;
Cheong Soo PARK
Author Information
1. Department of Surgery, Yonsei University College of Medicine, Seoul, Korea. cspark1@yuhs.ac
- Publication Type:Case Report
- Keywords:
Anaplastic transformation;
Papillary thyroid carcinoma;
Anaplastic thyroid carcinoma
- MeSH:
Humans;
Lymph Node Excision;
Lymph Nodes*;
Rare Diseases;
Thyroid Carcinoma, Anaplastic;
Thyroid Gland*;
Thyroid Neoplasms*
- From:Korean Journal of Endocrine Surgery
2008;8(3):210-214
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Anaplastic thyroid carcinoma (ATC) is a rare disease that shows very aggressive behavior. Most ATCs arise from pre-existing thyroid carcinomas. However, anaplastic transformation occurring in metastatic cervical nodes is extremely rare. We report herein on 3 cases of anaplastic transformation of metastatic lateral cervical lymph nodes from primary papillary thyroid carcinoma (PTC), which happened long after the initial surgical treatment. All the patients died of disease within 4 months in spite of aggressive treatment for the lesions. Our experience supports that appropriate lymph node dissection is mandatory at the time of initial surgery even for differentiated thyroid carcinomas.
