Recent Research Advances on Pediatric Myelodysplastic Syndrome.
10.7534/j.issn.1009-2137.2015.03.057
- Author:
Wei LIN
1
;
Run-Hui WU
2
Author Information
1. Center of Hematology and Oncology, Beijing Key Laboratory of Pediatric Hematology and Oncology Molecule, National Key Discipline of Pediatrics, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China.
2. Center of Hematology and Oncology, Beijing Key Laboratory of Pediatric Hematology and Oncology Molecule, National Key Discipline of Pediatrics, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China. E-mail: runhuiwu@hotmail.com.
- Publication Type:Journal Article
- MeSH:
Acute Disease;
Humans;
Myelodysplastic Syndromes
- From:
Journal of Experimental Hematology
2015;23(3):898-902
- CountryChina
- Language:Chinese
-
Abstract:
Myelodysplastic syndrome (MDS) is a group of highly heterogeneous, acquired hematopoietic stem/clonal disease, which is characterized by bone marrow dysplasia and high-risk conversion to acute leukemia, and is manifested by single or multi-lineage of cytopenia.The pathogenesis of MDS is complex, and has not yet been fully elucidated. Studies have shown that there are many differences between children and adults MDS.In this article the advances of studies on pediatric myelodysplastic syndrome are summaried.