Role of sulfogalactosylglycerolipid and sulfolipidimmobilizing protein 1 in sperm-egg plasma membrane interaction.
- Author:
Xiao-Mei FENG
1
;
Jun-Jun WANG
;
Yu-Feng HUANG
Author Information
1. Center of Medical Laboratory Science, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, Jiangsu 210002, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Carrier Proteins;
physiology;
Cell Membrane;
physiology;
Female;
Galactolipids;
physiology;
Humans;
Male;
Sperm-Ovum Interactions;
physiology
- From:
National Journal of Andrology
2003;9(9):697-699
- CountryChina
- Language:Chinese
-
Abstract:
Sperm-egg plasma membrane interaction is one of the important steps of mammalian fertilization. Many sperm and egg surface proteins are reported to be involved in sperm-zona pellucida interaction. Sulfogalactosylglycerolipid(SGG) is the major sulfoglycolipid in the germ cells of mammalian and lower vertebrates, mainly in the sperm head. It is a differentiation marker in spermatogenesis restricted to the zygotene and early pachytene spermatocytes. Sulfolipidimmobilizing protein 1 (SLIP1) is the major sulfoglycolipid of mammalian germ cells and eggs, with the same localization as SGG in the sperm. SLIP1 binds specificity to SGG, both playing a vital role in sperm-egg interaction. This article is aimed at reviewing the localization of SGG and SLIP1 in the germ cell surface and their role and related mechanism in gamete formation.
