Expression changes of tau protein and microtubule-associated proteins in testis intersitium of rats.
- Author:
Zilong LIU
1
;
Gang WANG
;
Wanhong ZHANG
;
Shenghong LIU
;
Xiaoli WANG
;
Fang WANG
;
Xuejun KANG
Author Information
- Publication Type:Journal Article
- MeSH: Aging; metabolism; Animals; Immunohistochemistry; Male; Microtubule-Associated Proteins; analysis; Rats; Rats, Sprague-Dawley; Testis; chemistry; tau Proteins; analysis
- From: National Journal of Andrology 2004;10(1):35-38
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo examine the expression of the tau protein and microtubule-associated proteins in the testis interstitium of aged and young rats.
METHODSSprague-Dawley male rats were divided into a young group(6 months, n = 10) and an aged group(28 months, n = 10). The two steps immunohistochemistry method with the antibody against tau protein and MAP alpha was performed on the testis tissues of the rats.
RESULTSThe results showed that the immunoreactive cells of tau protein of the testis interstilial of the aged rats obviously increased(P < 0.001) than those of the young, while the immunoreactive cells of the microtubule-associated proteins decreased(P < 0.01) in the aged.
CONCLUSIONThe changes in the expression of the tau protein and microtubule-associated proteins may be related to the aging process of the testis.
