Progress in researches on sperm antigen fertilin beta.
- Author:
Jun ZHANG
1
;
Yanfeng LI
Author Information
1. Department of Urology, Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing, 400042, China.
- Publication Type:Journal Article
- MeSH:
ADAM Proteins;
Animals;
Contraception, Immunologic;
Fertilins;
Fertilization;
Humans;
Male;
Membrane Glycoproteins;
chemistry;
genetics;
physiology;
Metalloendopeptidases;
chemistry;
genetics;
physiology;
Vaccines;
immunology
- From:
National Journal of Andrology
2004;10(1):52-58
- CountryChina
- Language:Chinese
-
Abstract:
Fertilin beta plays an important role in fertilization by its disintegrin domain as a sperm-specific antigen. This paper reviews its structure, localization and roles in fertilization, and suggests that fertilin beta, as an important target antigen, has a very promising value in the development of human immunocontraceptive vaccine.
