Two Cases of Rapidly Progressive Glomerulonphritis treated with ?ulse Methylprednisolone Therapy.
- Author:
Soon Pyo CHUNG
1
;
Heung KIM
;
Kew Taek KIM
Author Information
1. Department of Pediatrics, St. Benedict Hospital, Busan, Korea.
- Publication Type:Original Article
- MeSH:
Creatinine;
Follow-Up Studies;
Humans;
Methylprednisolone*
- From:Journal of the Korean Pediatric Society
1980;23(5):406-412
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Tow patients with severe glomerulonephitis and their serum creatinine clearance of 6.0ml/min/1.73m2 in case 2 were treated with high dosage intravenous methylprednisolone, 30mg/kg given over one hour period on each of six slternate days. Follwing the ?ulse therapy, both patients with rapidly deteriorathin renal funtion began to inprove and theit serum creatinine clearance levels showed over douvble by sixdays In both patients treated early in the curse of their disease, creatinine clearance increased to 80ml/min/1.73m2 in case 2 after one year follow-up and in recent study, clinical and laboratory findings are within normal limit.
