Efficacy of local injection of bacillus calmette-guerin polysaccharide nucleic acid following CO2 laser resection on condyloma acuminatum.

Author: Xiao YU ¹ ; Zhangqun YE ; Weimin YANG ; Rongjin DENG
Author Information

1. Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Publication Type:Clinical Trial
MeSH: Adjuvants, Immunologic; administration & dosage; Adult; Aged; BCG Vaccine; administration & dosage; Condylomata Acuminata; therapy; Female; Humans; Laser Therapy; Male; Middle Aged; Nucleic Acids; administration & dosage; Polysaccharides; administration & dosage
From: National Journal of Andrology 2004;10(2):117-121
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo observe the efficacy of local injection of bacillus calmette-guerin polysaccharide-nuclear acid (BCG-PSN) following CO2 laser resection on condyloma acuminatum (CA).
METHODSOne hundred and six patients with CA were randomized into BCG-PSN group (60 cases) and interferon group (46 cases), treated respectively with BCG-PSN local injection and interferon subcutaneous injection following CO2 laser resection and followed up for 3 months.
RESULTSThe healing rate of the BCG-PSN group was 88.3% and that of the interferon group was 71.7%.
CONCLUSIONThe BCG-PSN local injection following CO2 laser resection is effective for CA patients.