Efficacy and safety of intraprostatic injection of chuanshentong for chronic abacterial prostatitis/chronic pelvic pain syndrome.
- Author:
Wei WANG
1
;
Huixu HE
;
Weilie HU
;
Xiaoming ZHANG
;
Yuanli WANG
Author Information
- Publication Type:Clinical Trial
- MeSH: Adult; Chronic Disease; Double-Blind Method; Drugs, Chinese Herbal; adverse effects; therapeutic use; Humans; Injections; Male; Middle Aged; Pelvic Pain; drug therapy; Prostatitis; drug therapy
- From: National Journal of Andrology 2004;10(3):182-187
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the efficacy and safety of intraprostatic injection of Chuanshentong in the treatment of chronic abacterial prostatitis/chronic pelvic pain syndrome(CAP/CPPS).
METHODSRandomized, double blinded, placebo controlled trials were carried out from September 2002 to March 2003. A total of 38 patients with diagnosed CAP/CPPS, 24 experimental and 14 controls, were analyzed. In the trial group, 6 ml of mixed solution of Chuanshentong and lidocaine was transperineally injected into one lobe of the prostate, once a day for 6 days. Likewise, the control group was treated with placebo containing lidocaine. The efficacy was evaluated by the NIH Chronic Prostatitis Symptom Index(CPSI) after a 6-week follow-up. The main semen parameters before and after 3-month treatment were compared.
RESULTSIn the trial group, 13 cases (56.5%) were completely cured, 5 cases(21.7%) showed remarkable effect, and 4 cases (17.4%) were improved. While in the control group, effectiveness was shown in only 2 cases (15.4%), and improvement in 3 cases (23%). CPSI scores decreased significantly after treatment(95% of confidence interval: 17.97-23.08). Chuanshentong solution had no obvious impact on the main semen parameters. No severe adverse effects were observed.
CONCLUSIONTransperineal intraprostatic injection of Chuanshentong is a safe and effective method for the treatment of CAP/CPPS.
