Regional Distribution of Lactate Dehydrogenase Isozymes in Rabbit Brain.

Author: Kyung Ah PARK ¹
Author Information

1. Department of Anatomy, Yonsei University College of Medicine, Seoul, Korea.
Publication Type:Original Article ; Research Support, Non-U.S. Gov't
MeSH: Animal; Brain/enzymology*; Isoenzymes; Lactate Dehydrogenase/analysis*; Rabbits; Tissue Distribution
From:Yonsei Medical Journal 1980;21(1):1-8
CountryRepublic of Korea
Language:English
Abstract: The resolution of lactate dehydrogenase isozymes in tissue samples obtained from various regions of the rabbit brain was carried out by cellulose acetate electrophoresis. 1) Most regions of the brain showed an H-type isozyme pattern. 2) Five clear1y differentiated patterns of isozyme activity were found throughout the entire cerebral cortex with no difference between the lobes of the cerebral cortex. 3) All 5 patterns were found in the upper brain, while 4 patterns-LDH-1, 2, 3 and very 1ow activity of LDH-4 were found in the lower brain.