Clinical and subclinical characteristics of dry mouth in Gougerot-Sj\xf6gren syndrome after rheumatoid arthritis
- Author:
Lan Thi Ngoc Nguyen
;
Ngoc Vinh Nguyen
- Publication Type:Journal Article
- Keywords:
Gougerot-Sj\xf6gren syndrome;
rheumatoid arthritis;
dry mouth;
diagnosis
- MeSH:
Arthritis;
Rheumatoid/ pathology;
diagnosis;
Sjogren's Syndrome/ pathology;
diagnosis;
Xerostomia/ pathology;
diagnosis
- From:Journal of Medical Research
2007;53(5):129-133
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Background: Gougerot-Sj\xf6gren syndrome is an autoimmune disorder with two remarkable symptoms such as dry eyes and dry mouth. Objective: To study the symptoms of dry mouth of Gougerot-Sj\xf6gren syndrome after rheumatoid arthritis; To evaluate clinical and subclinical manifestations of dry mouth. Subjects and method: A prospective, descriptive, cross-sectional study included 160 patients with rheumatoid arthritis, who treated at Department of Rheumatology of Bach Mai hospital, from 1998 to 2003. The patients were divided into 2 groups: 60 patients with Gougerot-Sj\xf6gren syndrome and 100 patients without Gougerot-Sj\xf6gren syndrome. Results: The average age of patients with Gougerot-Sj\xf6gren syndrome was 54.55 \xb1 10.91 years. The mean time of having dry mouth was 8.65 \xb1 8.39 months. Clinical manifestations of dry mouth were sensation of dry mouth (90%), lost of saliva (80%), drink a lot of water while eating (58.3%), enlargement of parotid glands (15%). Degrees of dry mouth were mild and moderate (36.7%), severe (53.3%). 93.3% of patients decreased total salivary flow.82% of patients had 3 and 4 anatomopathologic stages according to Chilsom classification. Conclusion: Incidence of symptoms of dry mouth was higher significantly in the rheumatoid arthritis patients with Gougerot-Sj\xf6gren syndrome than those without Gougerot-Sj\xf6gren syndrome.
