Hemolysis test of the five kinds of impeller blood pumps in vitro.
- Author:
Bingyi LI
1
;
Changyan LIN
;
Yiling JIANG
;
Jing WANG
;
Lizheng CHEN
Author Information
1. Beijing Heart Lung & Blood Vessel Disease Research Institute, An Zhen Hospital, Beijing 100029.
- Publication Type:Journal Article
- MeSH:
Animals;
Blood Flow Velocity;
Evaluation Studies as Topic;
Heart-Assist Devices;
adverse effects;
Hemolysis;
In Vitro Techniques;
Sheep;
Temperature
- From:
Journal of Biomedical Engineering
2002;19(3):479-482
- CountryChina
- Language:Chinese
-
Abstract:
Hemolysis caused by blood pumps is a very important characteristic. In vitro hemolysis test circuits were constructed to operate the model I centrifugal pump, the model II axial flow pump, the magnetic coupling pump and the model I & II spiral mixed pump. The output of all pumps was set at flow 5 L/min, an average pressure of 100 mmHg. Experiments were conducted for 4 hours at room temperature(25 degrees C) with 500 ml fresh anticoagulant sheep blood. Blood samples were taken for plasma free-hemoglobin measurement, and the change in temperature at the pump outlet port was measured during the experiment. Calculate the normalized index of hemolysis (NIH). The results showed that there was no relationship either between the pump rotational speed and the NIH in five types of blood pumps, or between change in temperature at the pump outlet port and NIH. The dynamic fluid field caused by pump design and structure could be the main cause of blood damage.
