Relationship between body mass index and outcome of in vitro fertilization and embryo transfer cycle in patients with endometriosis.
- Author:
Zhenhui HOU
1
;
Song QUAN
;
Weiping QIAN
;
Weihong YANG
;
Liyan XU
;
Yanpei CAO
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Body Mass Index; Embryo Transfer; methods; Endometriosis; therapy; Female; Fertilization in Vitro; Humans; Pregnancy; Pregnancy Rate; Retrospective Studies
- From: Journal of Southern Medical University 2014;34(3):379-382
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the relationship between body mass index (BMI) and clinical outcomes of in vitro fertilization and embryo transfer (IVF/ICSI-ET) cycles in patients with endometriosis.
METHODSWe retrospectively analyzed the data of infertile women with endometriosis undergoing 244 IVF/ICSI-ET cycles between January, 2011 and August, 2012. The patients, categorized into 3 groups with mild endometriosis, moderate to severe endometriosis, and no endometriosis (control), underwent a long protocol, and the relationship of the general conditions, dose of gonadotropin, days of stimulation, BMI, number of oocytes retrieved and embryos transferred with the outcome of IVF were analyzed.
RESULTSThere was significant difference between moderate to severe endometriosis group and the control group in the number of ampules, oocytes retrieved and embryos transferred. The patients with moderate or severe endometriosis had significantly lower BMI and clinical pregnancy rate than those with mild or no endometriosis.
CONCLUSIONEndometriosis is inversely correlated with BMI, and BMI of the patients with endometriosis may affect the pregnancy rate of IVF cycles.