Myoepithelial carcinoma of the salivary glands: behavior and management.
- Author:
Guangyan YU
1
;
Daquan MA
;
Kaihua SUN
;
Tiejun LI
;
Ye ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Female; Humans; Male; Middle Aged; Myoepithelioma; mortality; therapy; Prognosis; Retrospective Studies; Salivary Gland Neoplasms; mortality; therapy
- From: Chinese Medical Journal 2003;116(2):163-165
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo investigate the biological behavior and proper management of myoepithelial carcinomas of salivary glands.
METHODSTwenty-seven cases of myoepithelial carcinoma of salivary glands were retrospectively studied and their detailed clinical and follow-up data were presented.
RESULTSThe subjects consisted of 17 men and 10 women aged 16 to 73 years (mean age: 51 years). The parotid gland was the most common site (n = 14) of cancer. Clinical features included extensive local growth, invasion of the surrounding tissues, infrequent cervical lymph node metastasis but high rates of distant metastasis, frequent/multiple recurrences and poor prognosis.
CONCLUSIONSMyoepithelial carcinomas of the salivary gland should be classified as high-grade malignancies. Early and radical surgery with close follow-up are essential for achieving favorable outcomes. Radiotherapy appears to be non-sensitive and elective neck dissection is generally unnecessary.
