Studies on chemical constituents of cytotoxic fraction from leaves of Elaeagnus pungens.
- Author:
Xin ZHAO
1
;
Rui-Liang ZHU
;
Biao JIANG
;
Hao HUANG
Author Information
- Publication Type:Journal Article
- MeSH: Caffeic Acids; chemistry; isolation & purification; pharmacology; Cell Proliferation; drug effects; Elaeagnaceae; chemistry; HeLa Cells; cytology; Humans; Kaempferols; chemistry; isolation & purification; pharmacology; Parabens; chemistry; isolation & purification; pharmacology; Plant Leaves; chemistry; Plants, Medicinal; chemistry; Quercetin; analogs & derivatives; chemistry; isolation & purification; pharmacology
- From: China Journal of Chinese Materia Medica 2006;31(6):472-474
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents possessing cytotoxicity activity from Elaeagnus pungens.
METHODThe constituents were separated through repeated chromatographic methods and their structures were elucidated by spectral analysis.
RESULTFive compounds were isolated from the ethyl acetate ether extract of leaves of E. pungens. Their structures were elucidated as 4-hydroxybenzoic acid (1), 3, 3'-dimethoxyquercetin (2), caffeic acid methyl ester (3), methyl 3, 4-dihydroxybenzoate (4), spingic acid (5), 4-methoxylbenzoic acid (6), 3-methylkaempferol (7), kaempferol-3-O-beta-D-glucoside (8), dausosterol (9).
CONCLUSIONCompounds 1-8 were isolated from this plant for the first time.
