Constituents in the alkaloid fraction of Kushen decoction.
- Author:
Bin LIU
1
;
Ren-Bing SHI
Author Information
- Publication Type:Journal Article
- MeSH: Alkaloids; chemistry; isolation & purification; Drug Combinations; Drugs, Chinese Herbal; chemistry; isolation & purification; Piperidines; chemistry; isolation & purification; Plants, Medicinal; chemistry; Quinolizines; chemistry; isolation & purification; Rehmannia; chemistry; Scutellaria baicalensis; chemistry; Sophora; chemistry
- From: China Journal of Chinese Materia Medica 2006;31(7):557-560
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents of the alkaloid fraction of Kushen decoction.
METHODConstituents were isolated by different kinds of column chromatography and their structures were elucidated with spectral methods.
RESULTEight compounds were isolated and identified as matrine (I), sophoridine (II), sophocarpine (III), sophoramine (IV), oxymatrine (V), oxysophocarpine (VI), aloperine (VII) and sparteine (VIII).
CONCLUSIONAll these compounds were isolated from Kushen decoction for the first time. Aloperine was found firstly in Sophora flavescens, or Scutellaria baicalensis, or Rehmannia glutinosa which constituted Kushen decoction.
