Supercritical fluid extraction of paeonol from Liuwei Dihuang pill.
- Author:
Yi-ling CHANG
1
;
Ben LIU
Author Information
- Publication Type:Journal Article
- MeSH: Acetophenones; isolation & purification; Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; methods; Drug Combinations; Drugs, Chinese Herbal; chemistry; Plants, Medicinal; chemistry; Reproducibility of Results; Tablets
- From: China Journal of Chinese Materia Medica 2006;31(8):653-655
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the method of extraction of active ingredient from complex Chinese patent medicine.
METHODSupercritical fluid extraction (SFE) has been used to extract paeonol from Liuwei Dihuang pill and HPLC was used to analyze the extracts.
RESULTThe methanol modified supercritical CO2 (0.4 mL x min(-1)) can effectively extract paeonol from Liuwei Dihuang pill.
CONCLUSIONSFE-HPLC method of off-line for analysis of extract was simple, quick and accurate.