Studies on chemical constituents in root of Phlomis medicinalis I.
- Author:
Zhen-xi YU
1
;
Gang-li WANG
;
Ciren BIANBA
;
Rui-chao LIN
Author Information
- Publication Type:Journal Article
- MeSH: Benzofurans; chemistry; isolation & purification; Glucosides; chemistry; isolation & purification; Phlomis; chemistry; Plant Extracts; chemistry; isolation & purification; Plant Roots; chemistry; Plants, Medicinal; chemistry; Pyrans; chemistry; isolation & purification; Terpenes; chemistry; isolation & purification
- From: China Journal of Chinese Materia Medica 2006;31(8):656-658
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents in root of Phlomis medicinalis.
METHODThe compounds were isolated and repeatedly purified on macroporous resin, silica gel column chromatography, TLC and Prep-HPLC and the structures were elucidated by physico-chemical properties and NMR spectra.
RESULTEight compounds were obtained and elucidated as 5-Hydroxy-7-methoxy-4, 6-dimethylphthalide (1), 4-hydroxymethyl-2-furaldehyde (2) and six iridoid glucosides: 6-O-acetyl-shanzhiside methyl ester (3), 8-O-acetyl-shanzhiside methyl ester (4), shanzhiside methyl ester (5), sesamoside (6), phloyoside II (7) and dehydropentstemoside (8).
CONCLUSIONAll the compounds were isolated from the plant for the first time and 1 and 3 were obtained from the plants of Phlomis for the first time.
