Pathogenic significance and possible pathogenic mechanism of human endogenous viruses in development of schizophrenia.
- Author:
Rong DA
;
Jian-Kang REN
- Publication Type:Journal Article
- MeSH:
Animals;
Environment;
Humans;
Schizophrenia;
etiology;
genetics;
immunology;
virology;
Viruses;
genetics
- From:
Chinese Journal of Virology
2014;30(1):98-102
- CountryChina
- Language:Chinese
-
Abstract:
The association between psychogenic illness and human endogenous viruses (HEVs), including human endogenous retrovirus and Borna disease virus, remains unclear. As the component of human genome, HEVs may become the joint of various pathogenic factors of schizophrenia (SZ), such as heredity, environment, and immunity. In this review, we strive to uncover the clinical and laboratory evidence for the roles and possible pathogenic mechanism of HEVs in the development of SZ.
