Study on detection of samples of Rh-weak D and Del.
- Author:
Xiao-Zhu WANG
1
;
Jiong-Cai LAN
;
Xu-Hua WU
;
Hua-You ZHOU
;
Wei-Jia LIU
;
Dan LIU
;
Cun-Sheng QI
;
Feng-Qin ZENG
;
Ke-Qing DU
Author Information
1. Laboratory of Blood Transfusion, Qinhuangdao Blood Center, Qinhuangdao 066001, China.
- Publication Type:Journal Article
- MeSH:
Blood Donors;
Blood Grouping and Crossmatching;
methods;
standards;
Epitopes;
immunology;
Erythrocytes;
immunology;
Humans;
Rh-Hr Blood-Group System;
blood;
immunology
- From:
Journal of Experimental Hematology
2005;13(3):509-511
- CountryChina
- Language:Chinese
-
Abstract:
To study the detection of weak D and Del from samples initially screened RhD(-), RhD phenotype was initially screened by routine serological test, out of which weak D phenotype was detected by indirect antiglobulin test (IAT) and Del phenotype was detected by chloroform-trichloroethylene absorption-elution test. The results showed that 56 samples were RhD(-) confirmed by routine serology test, which were screened out of 26 200 donors, among them 5 samples were typed as weak D by IAT and 9 cases samples were typed as Del by absorption-elution test. In conclusion, the samples which typed as RhD(-) by routine serological test must be identified by IAT and chloroform-trchloroethylene absorption test is order to detect weak D and Del phenotype. It is important for clinical transfusion safely.
