Reserch progresses in effect of traditional Chinese medicines on cytochrome P450 activities from 2000--2011.
- Author:
Xinbao YANG
1
;
Jianxun LIU
Author Information
1. Beijing University of Chinese Medicines, Beijing 100029, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Cytochrome P-450 Enzyme System;
metabolism;
Drugs, Chinese Herbal;
pharmacokinetics;
Humans;
Medicine, Chinese Traditional;
methods
- From:
China Journal of Chinese Materia Medica
2012;37(7):871-877
- CountryChina
- Language:Chinese
-
Abstract:
The interaction between drugs is mainly guided by cytochrome P450 (CYP) enzyme system. CYP participates in the physical biotransformation of a majority of endobiotic and xenobiotic molecules, especially drugs. It is quite crucial and urgent to investigate drugs effect on CYP before clinical application to ensure the clinical safety and pharmacy validity. In this paper, the progresses on the effect of traditional Chinese medicines on cytochrome P450 activities from 2000-2011 are reviewed.
