Simultaneous determination of three coumarins in Angelica dahurica var. formosana by QAMS.
- Author:
Fang YANG
1
;
Li WAN
;
Yichen HU
;
Wei LV
;
Yi ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Angelica; chemistry; Chromatography, High Pressure Liquid; Coumarins; chemistry; Drugs, Chinese Herbal; chemistry; Furocoumarins; chemistry; Reference Standards
- From: China Journal of Chinese Materia Medica 2012;37(7):956-960
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo develop a quantitative analysis of multi-components by single marker(QAMS) method for simultaneous determination of three coumarins in Angelica dahurica var. formosana, by using one standard substance.
METHODWith imperatorin as internal reference standard, and 2 relative correction factors (RCF) to imperatorin were calculated within certain ranges. Their contents in 20 batches of samples, collected from different areas, were determined by both external standard method and QAMS. The method was evaluated by comparison of the quantitative results between the two methods.
RESULTNo significant differences were found in the quantitative results of three coumarins in 20 batches of A. dahurica var. formosana determined by the two methods (RSD < 5%).
CONCLUSIONQAMS is feasible and suitable for quality control of A. dahurica var. formosana.
