Acute angiographic and clinical outcomes of patients with calcified chronic total occlusion underwent ercutaneous coronary intervention
10.3321/j.issn:0253-3758.2008.08.008
- VernacularTitle:冠状动脉慢性完全闭塞合并钙化病变的介入治疗
- Author:
Ya-Ling HAN
1
;
Hui-Qiang ZHAO
;
Shou-Li WANG
;
Quan-Min JING
;
Ying-Yan MA
;
Bo LUAN
;
Geng WANG
;
Fei LI
Author Information
1. 沈阳军区总医院
- Keywords:
Coronary disease;
Angioplasty,transluminal,percutaneous coronary;
Chronictotal occlusion;
Calcification
- From:
Chinese Journal of Cardiology
2008;36(8):706-709
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the in-hospital outcome of patients with calcified chronic total occlusion (CTO) lesion underwent percutaneous coronary intervention (PCI) . Methods The clinic and lesion characteristics as well as acute PCI outcome were analyzed in 726 patients with calcified CTO [624 detected by coronary angiography (CAG) and 102 detected by intravascular unltrasound (IVUS)] and received PCI therapy from June 1995 to February 2007 in our department. Results There were 728 diseased vessels with 732 lesions in these patients. Total procedure success rate (80. 6% vs. 89. 2%, P <0. 05) and the lesion success rate (80. 2% vs. 88.2%, P < 0. 05 ) were significantly lower in calcified CTO detected by CAG compared to that detected by IVUS. The causes of procedure failures in CAG detected patients were as follows: 87 guide failure, 21 balloon failure, 8 procedure related complications and 5 low TIMI blood flow (grade 2) at the end of PCI procedure. The causes of procedure failures in IVUS detected patients were as follows: 7 guide wire failure, 2 balloon failure, 1 procedure related complications and 1 patient with low TIMI blood flow (grade 2). The in-hospital major adverse cardiac events (MACE) rate was 1.1% in CAG detected calcified CTO and 1.0% in IVUS detected calcified CTO (P 0. 05). Conclusion PCI therapy resulted in satisfactory procedure success rate and in-hospital outcome for patients with calcified CTO and IVUS is helpful for further increasing the PCI procedure success rate in patients with calcified CTO.