Association between fasting plasma glucose and the 5 years outcome post PCI in aged patients with coronary artery disease
10.3321/j.issn:0253-3758.2008.08.009
- VernacularTitle:空腹血糖水平与经皮冠状动脉介入治疗五年预后的关系
- Author:
Hai-Yan SU
1
;
Chang-Yu PAN
;
Min LIU
;
Meng-Meng JIN
Author Information
1. 解放军总医院
- Keywords:
Blood glucose;
Angioplasty,transluminal,percutaneous coronary;
Coronaryrestenosis;
Adverse cardiac events
- From:
Chinese Journal of Cardiology
2008;36(8):710-713
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the association between fasting plasma glucose (FPG) and 5 years outcome post PCI in aged patients with coronary artery disease (CAD). Methods A total of 269 patients (mean age 63.8±9.4 years, 236 males) with CAD underwent PCI between January 2000 and December 2001 were followed up and data on angiographic restenosis, the major adverse cardiac events, the cumulative survival rates and the correlated risk factors were collected and analyzed. Patients were divided into 4 groups according to the levels of their FPG at baseline (group 1:FPG < 5.6 mmol/L; group 2:5. 6 mmol/L≤FPG <6. 1 mmol/L;group 3:6. 1 mmol/L≤FPG <7.0 mmol/L;group 4:FPG≥7.0 mmol/L). Results At the end of the 5 years follow-up, the incidences of major adverse cardiac events, target lesion revascularization, recurring angina pectofis and angiographic restenosis of group 2 were significantly higher than those of group 1 (P < 0. 05) and similar as those in group 3 (P 0.05). The cumulative survival rates of cardiovascular events of group 2, group 3 and group 4 were all significantly decreased compared with group 1 ( P < 0. 05 ). The logistic regression model analysis showed that FPG was an independent risk factor for angiographic restenosis, incidence of major adverse cardiac events, all-cause mortality and recurring angina pectoris (P < 0. 05 ). Conclusion FPG≥5.6 mmol/L and over is associated with increased incidences of major adverse cardiac events in aged patients with CAD who underwent PCI.
